In this review:
This review focuses on important and often flawed aspects of published randomised controlled
trials (RCTs). Many of these failings occur within key features of the design of the study. These
features are often fundamental to the principles of medical research as exemplified in RCTs, e.g.
blinding and representativeness of participant samples. These weaknesses may be unavoidable
in some contexts and in others may have no significant clinical ramifications.
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